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Good Sam stars Sophia Bush as Dr. Sam Griffith, a gifted young heart surgeon looking to come into her own personally and professionally. Sam is overshadowed and undermined by her renowned and arrogant boss Dr. Rob "Griff" Griffith (Jason Isaacs), who also happens to be her father. The tension is building. Good Sam premieres Wednesday January 5 on CBS.。一条庞大的蛇从实验室逃亡之后潜入城市下水道之内，并伤害许多无辜的人，已对整个城市构成威胁和恐慌。联帮调查局官员和科学家决定使用最原始的办法--以暴制暴来铲除大蛇，科学家将一枚芯片置入一条蟒蛇脑中，只允许躇蛇看见逃亡下水道的大蛇.同时,一群为了赚钱的猎人也正在尝试使用各种方法来杀蛇，然而，此大蛇也有着非常的智慧，甚至有它的阴谋--报复人类，连蟒蛇也不能将它制服……。